ICSI, Intracytoplasmic Sperm Injection Treatment at SWCIC
Intracytoplasmic sperm injection (ICSI) is a laboratory procedure, where eggs and sperms are collected from bodies of male and female partners and then the sperm is released into the uterus.
ICSI ( Intracytoplasmic Sperm Injection )
ICSI treatment hyderabad
Along with the strong support and dedication from our team, the fertility treatment options are the other factor that makes us the best and renowned test tube baby center in Hyderabad India .
In conventional ICSI
In conventional ICSI, the embryologist selects the most normal-looking motile sperm using a microscope that magnifies the sample up to 400 times. The sperm is then injected into the egg and then placed in the incubator for further development.
What is Intracytoplasmic sperm injection (ICSI)
Intracytoplasmic sperm injection (ICSI) is a lab procedure done by the embryologists where the sperms are first collected through a needle,then the eggs and few sperms are collected from female and male partners , it is then inserted into the woman’s uterus. ICSI is also similar to IVF though the purpose is the same the method of fertilisation differs.
How is ICSI Performed?
The fertilized egg is collected and using a thin & sharp needle sperm is collected. The needle is then inserted through the eggshell into the cytoplasm of the egg. Once the sperm is released into the cytoplasm, the needle is ejected out. The procedure is followed up to examine the process of fertilization. After ICSI is done and the fertilization is fruitful, the embryo is then placed into the woman’s uterus. The woman has to check if she experiences signs of pregnancy. Also a blood test could to be to figure out if the implantation has been successful or not. Regular shots have to taken and the woman has to take proper rest refraining from stressful activities.
Why is ICSI Done
ICSI is done to treat high level male infertility , it’s a condition when there are less sperm counts. The unfertilized sperms cannot move by themselves hence ICSI is the option to fertilize the egg using the ICSI procedure . ICSI is done at times if In Vitro Fertilization IVF has not been successful. It is also done when the partners would like to examine any abnormalities or genetic issues arising in the embryo. In ICSI procedure only a single sperm is used to fertilize one egg. Hence there is no possibility for contamination through another sperm.
The Success Rate of Intracytoplasmic Sperm Injection (ICSI) Treatment
The chances to succeed differ from individuals. It’s important to consider the age of the woman, however approximately around 25% of woman conceive after one round of ICSI treatment .
ICSI Treatment Cost in Hyderabad
The cost of ICSI depends on the fertility specialist experience and location of their clinic.
Risks of ICSI
Risks associated with ICSI are similar to IVF.
Superovulation with hormone treatment might lead to serious ovarian hyperstimulation syndrome . Your doctor can keep the risk at bay by close observation of the ovaries and frequent check up of hormone levels while the treatment is going on. The risk of becoming pregnant several times is directly linked to the number of embryos implants done to the woman’s uterus. Multiple pregnancies have greater chances of risks both the mother and the baby.
There are increased chances of threat or risk if conceived via ICSI i;e the baby has greater chances to have birth defects.
Technology is not same at all the time. It keeps on changing. The same way, on time updates are essential in the medical technologies as well. SWCIC- one of the best fertility centers in Hyderabad India, moves on with the advancements and the results are reflected in your smiles. Intracytoplasmic Morphologically Selected Sperm Injection IMSI is an example for that.
IMSI is a variation of ICSI that uses a high power light microscope (enhanced by digital imaging) to magnify the sperm sample over 6000 times. Sperms are then selected which have the most normally-shaped nuclei and least number of vacuoles. . The sperm is then injected into the egg and then placed in the incubator for further development.
The technique for examining sperm to use in IMSI was developed by a team led by Professor Bartoov. In 2002, his team used a high-powered microscope to determine which morphological characteristics of sperm might affect the outcome of ICSI. They suggested that ICSI pregnancy rates may be affected by subtle abnormalities in the shape of the sperm nucleus which embryologists may not detect during normal ICSI sperm selection.
In 2003, the same group published a study that looked at whether selecting sperm using IMSI improves the pregnancy rate in couples with repeated ICSI failures (compared to conventional ICSI).
Comparing results of ICSI with IMSI the pregnancy rate was significantly higher (60% vs 25%) and the miscarriage rate significantly lower (14% vs 40%) in the IMSI group compared to the conventional ICSI group.
There also is a significant improvement in implantation, pregnancy and birth rates using IMSI in patients with two or more previously unsuccessful IVF-ICSI attempts.
The pregnancy rates for patients were 29.8% in the IMSI group compared with 12.9% in the ICSI group. The miscarriage rates for these patients were also significantly lower in the IMSI group compared with the ICSI group
The use of IMSI is limited by the resources needed to carry out the technique. IMSI takes a minimum of 60 minutes and more often takes several hours. In addition the technique involves special equipment to reach the necessary magnification ( X6000), it has to be carried out by experienced embryologists trained in the specific technique, and this explains the significant extra cost of providing IMSI.
IVF-IMSI/ IVF-ICSI are very good options for
Tubal blockage or severe tubal damage
Ovarian failure (NO PERIODS),
Severe male factor infertility (less than 5 million/hpf)
Advanced stages of endometriosis
In women over 40 years old
In couples with a long duration of infertility (over 5 years)
How Does IMSI Treatment Work?
IMSI method describes the process of the IVF treatment which uses a high power light microscope to magnify the sperm sample more than 6,000 times than its actual size. This enables the doctor to identify the problems and subtle structural alterations. The embryologist then selects the sperm that has high motility level.
The IMSI treatment procedure is very similar to ICSI treatment. Fertility drugs are given to the woman to stimulate eggs in the ovaries. Once the follicle in an ovary grows between 17 to 22mm, the eggs are ready to collect. The HCG injection is given to the woman before the egg collection procedure takes place. The Human Chorionic Gonadotrophin (HCG) injection stimulate the eggs to mature.
The eggs are collected using the ultrasound-guided vaginal probe to locate the follicles and aspirates its contents under the light sedation. The collected eggs are then placed in the art laboratory. In this laboratory, the embryologist will inject the selected sperm into each egg.
IMSI Success Rates
IMSI had higher birth rates and pregnancy rates and lower miscarriage rates than ICSI and conventional IVF. Couples who underwent 2 or more unsuccessful IVF cycles, IMSI is the best option.
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